FARMACEVTSKA TEHNOLOGIJA PDF

Feature: for medium temperatures > °C or frequent changes in temperature. 0 to 1 bar – 0 to 60 bar relative, 0 to 1 bar – 0 to 25 bar absolute; Medium. HART® interface; Optional explosion protection [Ex ia] according to ATEX, GOST- R, DNV; Linearity %; Turn down: ; Simple operation with rotary knob. Get this from a library! Farmacevtska tehnologija. Del 1, Praktikum. [Julijana Kristl ; Jelka Šmid-Korbar; Stanko Srčič].

Author: Vozilkree Grosar
Country: Qatar
Language: English (Spanish)
Genre: Environment
Published (Last): 27 October 2010
Pages: 487
PDF File Size: 1.32 Mb
ePub File Size: 9.6 Mb
ISBN: 854-8-95468-733-7
Downloads: 99830
Price: Free* [*Free Regsitration Required]
Uploader: Mirg

Nivo | Farmacevtska tehnologija | Branže | JUMO

Your browser does not allow JavaScript! Pellet coating is commonly performed in a fluid bed coater such as a Wurster coater. Javascript is necessary for the proper functioning of this website. The effect tenhologija the Wurster gap and fluidizing air flow rate on gas-solidflow was analyzed in both simulations and experiments.

Javascript is necessary for the proper functioning of this website.

Voting is allowed only to logged in users. You have to log in to leave a comment. URL – Presentation file, Visit http: You have to log in to leave a comment.

Related Posts  FUTUHUL GHAIB EPUB

Your browser does not allow JavaScript!

Hydrophilic polyetilenglycol and hydrophobic meltable binder glyceryl palmitostearate were used for in situ fluidized hot melt granulation. Please enable JavaScript or use a modern browser. Computational fluid dynamics CFD simulations and experimental measurements of laboratory-scale Wurster coating were performed. The aim of this study was to investigate the influence of binder content, binder particle size, granulation time and inlet air flow rate on granule sizeand size distribution, granule shape and flowability, as well as on drug release rate.

CFD simulations were performed in a 2D axisymmetric space using the two-fluid model. URL – Presentation file, Visit http: Besides the nature and amount of binder, the mechanism of agglomerate formation seems to have an impact on drug dissolution rate.

Granule shape was affected by interplay of binder content, binder particle size and granulation time. Solid state analysis confirmed unaltered physical state of the granulate components and the absenceof interactions between the active and excipients.

Voting is allowed only to logged in users. Please enable JavaScript or use a modern browser. Binder content was shown to be important for narrow size distribution and goodflow properties.

Tlak | Farmacevtska tehnologija | Branže | JUMO

The results of the present study indicate that fluidized hot melt granulation is a promising powder agglomeration technique for spherical granules production. Experimentally, the draft tube two-phase flow farnacevtska evaluated by measuring the volume fraction of pellets within the draft tube and local particle velocities at the tube exit and by monitoring the local pressure drop fluctuations.

Related Posts  THE GREAT INDIAN MIDDLE CLASS PAVAN VARMA PDF

Granule size was mainly influenced by binder particle size. Your browser does not allow JavaScript!

A rather good agreement between the simulated and experimental results was observed and thus it can be assumeed that this particular simulation setup tehmologija a computationally reasonable tool that provides a valuable insight into the Wurster coating process due to the impact of two-phase flow properties on the process.

The results obtained indicate that conventional fluid bedgranulator may be suitable for production of highly spherical agglomerates,particularly when immersion and layering is dominant agglomeration mechanism.