Request PDF on ResearchGate | Anticorps antiphospholipides et hémostase | The antiphospholipid syndrome is characterized by recurrent thrombosis and. Download Citation on ResearchGate | Les anticorps antiphospholipides, signification et traitement | Antibodies The term antiphospholipid antibodies ( APLA). Request PDF on ResearchGate | Anticorps antiphospholipides en pratique | Antiphospholipid syndrome (APS) is an autoimmune disorder characterized by the.

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Ann Rheum Dis ; J Clin Invest ; Br Med J ; J Rheumatol ; The data of some large cohort followed prospectively such as the European cohort APS patients as well the data of some registries APS in children and patients with a catastrophic APS bring some new important information on the clinical aspects of the syndrome.

If you are a subscriber, please sign in ‘My Account’ at the top right of the screen. Br J Haematol ; J Immunol ; Koike T, Matsuura E. Anti-phospholipid antibodies are directed against a complex antigen that includes a lipid-binding inhibitor of coagulation: Inhibition of activating protein C and its cofactor protein S by antiphospholipid antibodies.

Amoura bL. Anticorps antiphospholipides en pratique. Antiphospholipid syndrome APS is an autoimmune disorder characterized by the occurrence of thrombotic or obstetrical events associated with the presence in the serum of patients of antibodies that are associated with thrombosis. Am J Med ; Human glycoprotein I as an anticardiolipin cofactor determined using delete mutants expressed by a baculovirus system. Contact an author Update request. Journal page Archives Contents list. Lupus ; 4: Finally this review will propose some algorithms to treat patients with APS.


Back to top About Swiss Copyright. The owners of this website hereby guarantee to respect the legal confidentiality conditions, applicable in France, and not to disclose this data to third parties. Despite numerous attempts, the assays that are available for the identification of antiphospholipid antibodies have not been standardized yet, which leads to high variability between reagents and laboratories. Asherson RA, Cervera R. Rev Med Intern ; Antiphospholipid syndrome, Thrombosis, Lupus anticoagulant, Antiphospholipid antibody.

Development of an ELISA for autoanbidodies to prothrombin showing their prevalence in patients with lupus anticoagulants.

Syndrome des anticorps antiphospholipides: beaucoup de nouveautés

It seems necessary to still perform anticardiolipin antibodies in case of pregnancy morbidity but not in case of thrombosis which raises the question of two separate clinical entities with different pathologic mechanisms.

Ann Intern Med ; Concerning the tests the search for lupus anticoagulant is now better defined.

Access to the PDF text. Thus, to optimize the biological monitoring of APS syndromes, it is mandatory to have consecutive samples analyzed in the same laboratory. Transfer of experimental antiphospholipid syndrome by bone marrow cell transplantation: Rev Med Intern ; 18 suppl.

Syndrome des anticorps antiphospholipides: beaucoup de nouveautés | Archive ouverte UNIGE

Syndrome des antiphospholipides, Thrombose, Lupus anticoagulant, Anticorps antiphospholipides. The pathogenesis of the antiphospholipid syndrome: Thrombosis, recurrent fetal loss, and thrombocytopenia: If you want to subscribe to this journal, see our rates You can purchase this item in Pay Per View: Recently some key papers and consensus have shed some new light on antiphospholipid syndrome APS.

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Cross-reaction between antibodies to oxidised low-density lipoprotein and to cardiolipin systemic lupus erythematosus. A modified antibeta2-glycoprotein I assay has been shown to be more specific for clinical complications.

Thrombosis in systemic lupus erythematosus despite circulating anticoagulants. Heterogeneity of anticardiolipin antibodies defined by the anticardiolipin cofactor. Access to the text HTML.

Induction of antiphospholipid syndrome in naive mice with mouse monoclonal and human polyclonal anticardiolipin antibodies. Arch Intern Med ; Arthritis Rheum ; Home Titles list Syndrome des anticorps antiphospholipides: Lupus ; 5: Contact Help Who are we?

Anticorps antiphospholipides en pratique Antiphospholipid antibodies in practice. Antivorps aZ. Pregnancy loss in the antiphospholipid-antibody syndrome: Induction of early atherosclerosis in LDL-receptor-deficient mice immunized with beta2-glycoprotein I.

Effects of monoclonal anticardiolipin antibody on pregnant mice. New methods of treatment in an experimental murine model of systemic lupus erythematosus induced by idiotypic manipulation. J Lab Clin Med ;